Similar to design research, clinical research involves the rigorous testing of solutions in appropriate settings, but this process is characterized by a different (often longer) timeframe, and incorporates the more stringent requirements appropriate for development of drugs, vaccines, etc. However, for interventions that pose a lower risk, clinical-level, randomized, controlled trials may be either unnecessary or inappropriate. For example, when developing a new vaccine, it is vital to follow the necessary rigor and requirements of the clinical trial process. But when developing or testing new medical recording mechanisms that allow parents and providers to better track the protection of a child’s health (e.g., the receipt of preventive services), the process can be more flexible. This provides the opportunity for design research to play a significant role. As designers and global health practitioners continue to work together, we hope that they will continue to identify the appropriate contexts in which design research can either support clinical studies, or provide the primary research platform.